Awareness of Aspirin’s Dual Role as an Anti-cancer Agent and Anti-thrombotic Agent and its Association with Medication Adherence to Low-Dose Aspirin: A Cross-Sectional Study
Hadhyah N. Alabdali1, Sarah S. Al- Harbi2, Layan Z. Sharalahi1, Razan A. Alghamdi1, Abrar M. Bokhari1, Yosra Z. Alhindi3*
1Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
2Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
3Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia
*Corresponding AuthorYzhindi@uqu.edu.sa, 00966504530609
Abstract:
Background:Aspirin is known to be an effective antithrombotic agent. Multiple studies have been studying its effect on cancer as colorectal cancer.
Aim:This study aimed to measure the Awareness of Aspirin's Dual Function as an Anti-Cancer Agent and Anti-Thrombotic among Residents of the Makkah region in the Kingdom of Saudi Arabia.
Methods:A cross-sectional study was conducted involving 490 participants from the Makkah region. Data collection was achieved through a self-reported online questionnaire and distributed via social media platforms from period of November 2024 until January 2025.
Results:Over 340 of the participants in this research have bachelor's degrees. However, while investigating awareness regarding the preventative effect of aspirin's dual role, only 8.4% were aware. Moreover, in terms of assessing the adherence level, we only included 306 (62.4%) of the participants who reported taking aspirin. The majority of them showed low adherence levels.
Conclusion:This study reveals a lack of awareness regarding of the knowledge abouts Aspirin as an Anti-Cancer and Anti-Thrombotic Agent among the residents of Makkah region, which appears to have an effect on medication adherence. Awareness promotion is essential to enhance public health outcomes.
Keywords:Aspirin; Anticancer; Antithrombotic, Makkah, Adherence.
Received: 28 Feb. 2026, Accepted: 22 Mar. 2026, Published: 27 Mar. 2026
How to Cite:
Alabdali, H. N., Al- Harbi, S. S., Sharalahi, L. Z., Alghamdi, R. A., Bokhari, A. M., Alhindi, Y. Z. Awareness of Aspirin’s Dual Role as an Anti-cancer Agent and Anti-thrombotic Agent and its Association with Medication Adherence to Low-Dose Aspirin: A Cross-Sectional Study.STJ,2026, 2, 13-23.
https://doi.org/10.70957/uqu.edu.sa/s.toxicology.s/stj.2025.2.2
Copyright: © 2025 by the authors. Licensee Umm Al-Qura University, Makkah, Saudi Arabia