السيرة الذاتية

المؤهلات

الدكتوراه

2004

‏علم الوراثة

كلية طب امبريال ، جامعة لندن | بريطانيا

الماجستير

1997

‏الكيمياء الحيوية

جامعة الملك سعود | المملكة العربية السعودية

الماجستير

1998

‏علم الوراثة

كلية طب امبريال ، جامعة لندن | بريطانيا

البكالوريوس

1412

‏المختبرات الطبية

جامعة أم القرى | المملكة العربية السعودية

الأبحاث العلمية

Novel LDLR Variant in Familial Hypercholesterolemia: NGS-Based Identification, In Silico Characterization, and Pharmacogenetic Insights

2023

مقال في مجلة | MDPI | Life (Basel)

أكثر

Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study

2024

مقال في مجلة | ELSEVIER SCIENCE INC | Lancet Diabetes Endocrinol

أكثر

Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

2021

مقال في مجلة | ELSEVIER SCIENCE INC | THE LANCET

أكثر

Deciphering the Structural and Functional Effects of the R1150W Non-Synonymous Variant in SCN9A Linked to Altered Pain Perception

2026

مقال في مجلة | MDPI | NeuroSci

أكثر

Identification and functional characterization of two rare LDLR stop gain variants (p.C231* and p.R744*) in Saudi familial hypercholesterolemia patients

2024

مقال في مجلة | MINERVA MEDICA | Panminerva Medica

أكثر

Prevalence of the Factor V Leiden Mutation Arg534Gln in Western Region of Saudi Arabia: Functional Alteration and Association Study With Different Populations

2019

مقال في مجلة | New York, N.Y. Raven 1995 | Clinical and Applied Thrombosis/Hemostasis

أكثر

Molecular Dynamics Simulation Reveals Exposed Residues in the Ligand-Binding Domain of the Low-Density Lipoprotein Receptor that Interacts with Vesicular Stomatitis Virus-G Envelope

2018

مقال في مجلة | Basel MDPI | VIRUSES

أكثر

Genotype Hemophilia Screening Program Identified 2 Novel Variants Including a Novel Variant (c.5816-2A > G) Causing a Pathogenic Variant of the Factor 8 Gene

2023

مقال في مجلة | SAGE PUBLICATIONS INC | CLINICAL AND APPLIED THROMBOSISHEMOSTAS

أكثر

Targeted next-generation sequencing reveals novel and known variants of thrombophilia associated genes in Saudi patients with venous thromboembolism

2024

مقال في مجلة | Elsevier | CLINICA CHIMICA ACTA

أكثر

Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis

2020

مقال في مجلة | DOVE MEDICAL PRESS LTD | International Medical Case Reports Journal

أكثر

Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia

2017

مقال في مجلة | KEAI PUBLISHING LTD | Non-coding RNA Research

أكثر

Association of functional variants and protein-to-protein physical interactions of human MutY homolog linked with familial adenomatous polyposis and colorectal cancer syndrome

2019

مقال في مجلة | KEAI PUBLISHING LTD | Non-coding RNA Research

أكثر

Prevalence of bleeding symptoms among young adults in Saudi Arabia, a national survey

2021

مقال في مجلة | LIPPINCOTT WILLIAMS & WILKINS | MEDICINE (Baltimore)

أكثر

Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and ˇ-cell initiation of specific antibodies to fight the infection

2019

مقال في مجلة | SPRINGER HEIDELBERG | Bio-Design and Manufacturing

أكثر

Compound A Increases Cell Infiltration in Target Organs of Acute Graft-versus-Host Disease (aGVHD) in a Mouse Model

2021

مقال في مجلة | MDPI | Molecules

أكثر

Identification of Novel and Known LDLR Variants Triggering Severe Familial Hypercholesterolemia in Saudi Families

2022

مقال في مجلة | BENTHAM SCIENCE PUBL LTD | Current Vascular Pharmacology

أكثر

Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing

2020

مقال في مجلة | F1000Research | F1000Research

أكثر

Anti-E. coli Immunoglobulin Yolk (IgY): Reduction of pathogen receptors and inflammation factors could be caused by decrease in E. coli load

2023

مقال في مجلة | CELLPRESS | Heliyon

أكثر

Familial Hypercholesterolemia in the Arabian Gulf Region: Clinical results of the Gulf FH Registry

2021

مقال في مجلة | PLOS | PLoS One

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema

2019

مقال في مجلة | ELSEVIER | Journal of Infection and Public Health

أكثر

Prevalence of bleeding symptoms among young adults in Saudi Arabia, a national survey

2021

مقال في مجلة | Lippincott | MEDICINE

أكثر

The Gulf Familial Hypercholesterolemia Registry (Gulf FH): Design, Rationale and Preliminary Results

2018

مقال في مجلة | Bentham Science Publishers | Current Vascular Pharmacology

أكثر

The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing

2020

مقال في مجلة | Frontiers | Frontiers in Genetics

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

2019

مقال في مجلة | Spandidos Publications | ONCOLOGY LETTERS

Strategies for Vaccination: Conventional Vaccine Approaches Versus New-Generation Strategies in Combination with Adjuvants

2021

مقال في مجلة | MDPI | Pharmaceutics

Effects of mineral trioxide aggregate, calcium hydroxide, biodentine and Emdogain on osteogenesis, Odontogenesis, angiogenesis and cell viability of dental pulp stem cells

2019

مقال في مجلة | BMC | BMC Oral Health

أكثر

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

2020

مقال في مجلة | SPANDIDOS PUBL LTD | Oncology Letters

أكثر

Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes

2021

مقال في مجلة | HINDAWI LTD | DISEASE MARKERS

أكثر

Strategies for Vaccination: Conventional Vaccine Approaches Versus New-Generation Strategies in Combination with Adjuvants

2021

مقال في مجلة | MDPI | PHARMACEUTICS

أكثر

The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing

2020

مقال في مجلة | FRONTIERS MEDIA SA | FRONTIERS IN GENETICS

أكثر

The Fetal Mouse Is a Sensitive Genotoxicity Model That Exposes Lentiviral-associated Mutagenesis Resulting in Liver Oncogenesis

2013

مقال في مجلة | CELL PRESS | Molecular Therapy

أكثر

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema.

2020

مقال في مجلة | Elsevier | Journal of Infection and Public Health

أكثر

Xanthomas Can Be Misdiagnosed and Mistreated in Homozygous Familial Hypercholesterolemia Patients: A Call for Increased Awareness Among Dermatologists and Health Care Practitioners.

2020

مقال في مجلة | UBIQUITY PRESS LTD | Global Heart

أكثر

The Gulf Familial Hypercholesterolemia Registry (Gulf FH): Design, Rationale and Preliminary Results.

2019

مقال في مجلة | BENTHAM SCIENCE PUBL LTD | Current Vascular Pharmacology

أكثر

Identification of six novel factor viii gene variants using next generation sequencing and molecular dynamics simulation.

2019

مقال في مجلة | The Polish Biochemical Society and the Polish Academy of Sciences | ACTA Biochimica Polonica

أكثر

Novel combined variants of LDLR and LDLRAP1 genes causing severe familial hypercholesterolemia.

2018

مقال في مجلة | Elsevier IRELAND LTD | Atherosclerosis

أكثر

Next generation DNA sequencing of atypical choroid plexus papilloma of brain: Identification of novel mutations in a female patient by Ion Proton.

2019

مقال في مجلة | SPANDIDOS PUBL LTD | Oncology Letters

أكثر

Microchimeric fetal cells cluster at sites of tissue injury in lung decades after pregnancy.

2008

مقال في مجلة | PMID: 18339261 | Reprod Biomed Online

أكثر

Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3.

2013

مقال في مجلة | SPRINGER HEIDELBERG | Biotech3

أكثر

Umbilical cord blood mesenchymal stromal cells are neuroprotective and promote regeneration in a rat optic tract model.

2009

مقال في مجلة | PMID: 19320003 | Exp Neurol

أكثر

Rat neurosphere cells protect axotomized rat retinal ganglion cells and facilitate their regeneration.

2009

مقال في مجلة | doi: 10.1089/neu.2008-0801 | J Neurotrauma

أكثر

Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype.

2009

مقال في مجلة | DOI: 10.4161/cc.8.7.8121 | Cell Cycle

أكثر

Reduction of aGVHD using chicken antibodies directed against intestinal pathogens in a murine model.

2017

مقال في مجلة | AMERICAN SOCIETY OF HEMATOLOGY | Blood

أكثر

Evidence of trem2 variant associated with triple risk of Alzheimer's disease

2014

مقال في مجلة | PUBLIC LIBRARY SCIENCE | PLoS One

أكثر

Next generation sequencing to identify novel genetic variants causative of autosomal dominant familial hypercholesterolemia associated with increased risk of coronary heart disease.

2015

مقال في مجلة | Elsevier | Gene

أكثر

Release of Vesicular Stomatitis Virus Spike Protein G-Pseudotyped Lentivirus from the Host Cell Is Impaired upon Low-Density Lipoprotein Receptor Overexpression.

2015

مقال في مجلة | AMERICAN SOCIETY OF MICROBIOLOGY | J Virol

أكثر

Identification of a recurrent frameshift mutation at the LDLR exon 14 (c.2027delG, p.(G676Afs*33)) causing familial hypercholesterolemia in Saudi Arab homozygous children.

2016

مقال في مجلة | ACADEMIC PRESS INC ELSEVIER SCIENCE | Genomics

أكثر

Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model.

2016

مقال في مجلة | BioMed Central | Journal of Experimental & Clinical Cancer Research

أكثر

Next-generation sequencing for molecular diagnosis of autosomal recessive polycystic kidney disease.

2016

مقال في مجلة | Elsevier | Gene

أكثر

Functional alterations due to amino acid changes and evolutionary comparative analysis of ARPKD and ADPKD genes.

2016

مقال في مجلة | Elsevier | Genomics Data

أكثر

Phytosterols as a natural anticancer agent: Current status and future perspective.

2017

مقال في مجلة | TAYLOR & FRANCIS INC | Biomedicine & Pharmacotherapy

أكثر

DNA mismatch repair MSH2 gene-based SNP associated with different populations.

2014

مقال في مجلة | SPRINGER HEIDELBERG | Molecular Genetics and Genomics

أكثر

Compound heterozygous LDLR variant in severely affected familial hypercholesterolemia patient.

2016

مقال في مجلة | ACTA BIOCHIMICA POLONICA | Acta Biochim Pol

أكثر

Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice

2008

مقال في مجلة | doi: 10.1016/j.ymthe.2005.10.003 | Molecular Therapy

أكثر

الكتب

Designing Lentiviral Gene Vectors. In Viral Gene Therapy Book

2011

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