CV | Faisal Ahmed Khalil Al-Allaf | Umm Al-Qura University

Qualifications

الدكتوراه

2004

علم الوراثة

كلية طب امبريال ، جامعة لندن | بريطانيا

الماجستير

1997

الكيمياء الحيوية

جامعة الملك سعود | المملكة العربية السعودية

الماجستير

1998

علم الوراثة

كلية طب امبريال ، جامعة لندن | بريطانيا

البكالوريوس

1412

المختبرات الطبية

جامعة أم القرى | المملكة العربية السعودية

Scientific Research

Novel LDLR Variant in Familial Hypercholesterolemia: NGS-Based Identification, In Silico Characterization, and Pharmacogenetic Insights

2023

مقال في مجلة | MDPI | Life (Basel)

Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study

2024

مقال في مجلة | ELSEVIER SCIENCE INC | Lancet Diabetes Endocrinol

Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

2021

مقال في مجلة | ELSEVIER SCIENCE INC | THE LANCET

Deciphering the Structural and Functional Effects of the R1150W Non-Synonymous Variant in SCN9A Linked to Altered Pain Perception

2026

مقال في مجلة | MDPI | NeuroSci

Identification and functional characterization of two rare LDLR stop gain variants (p.C231* and p.R744*) in Saudi familial hypercholesterolemia patients

2024

مقال في مجلة | MINERVA MEDICA | Panminerva Medica

Prevalence of the Factor V Leiden Mutation Arg534Gln in Western Region of Saudi Arabia: Functional Alteration and Association Study With Different Populations

2019

مقال في مجلة | New York, N.Y. Raven 1995 | Clinical and Applied Thrombosis/Hemostasis

Molecular Dynamics Simulation Reveals Exposed Residues in the Ligand-Binding Domain of the Low-Density Lipoprotein Receptor that Interacts with Vesicular Stomatitis Virus-G Envelope

2018

مقال في مجلة | Basel MDPI | VIRUSES

Genotype Hemophilia Screening Program Identified 2 Novel Variants Including a Novel Variant (c.5816-2A > G) Causing a Pathogenic Variant of the Factor 8 Gene

2023

مقال في مجلة | SAGE PUBLICATIONS INC | CLINICAL AND APPLIED THROMBOSISHEMOSTAS

Targeted next-generation sequencing reveals novel and known variants of thrombophilia associated genes in Saudi patients with venous thromboembolism

2024

مقال في مجلة | Elsevier | CLINICA CHIMICA ACTA

Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis

2020

مقال في مجلة | DOVE MEDICAL PRESS LTD | International Medical Case Reports Journal

Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia

2017

مقال في مجلة | KEAI PUBLISHING LTD | Non-coding RNA Research

Association of functional variants and protein-to-protein physical interactions of human MutY homolog linked with familial adenomatous polyposis and colorectal cancer syndrome

2019

مقال في مجلة | KEAI PUBLISHING LTD | Non-coding RNA Research

Prevalence of bleeding symptoms among young adults in Saudi Arabia, a national survey

2021

مقال في مجلة | LIPPINCOTT WILLIAMS & WILKINS | MEDICINE (Baltimore)

Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and ˇ-cell initiation of specific antibodies to fight the infection

2019

مقال في مجلة | SPRINGER HEIDELBERG | Bio-Design and Manufacturing

Compound A Increases Cell Infiltration in Target Organs of Acute Graft-versus-Host Disease (aGVHD) in a Mouse Model

2021

مقال في مجلة | MDPI | Molecules

Identification of Novel and Known LDLR Variants Triggering Severe Familial Hypercholesterolemia in Saudi Families

2022

مقال في مجلة | BENTHAM SCIENCE PUBL LTD | Current Vascular Pharmacology

Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing

2020

مقال في مجلة | F1000Research | F1000Research

Anti-E. coli Immunoglobulin Yolk (IgY): Reduction of pathogen receptors and inflammation factors could be caused by decrease in E. coli load

2023

مقال في مجلة | CELLPRESS | Heliyon

Familial Hypercholesterolemia in the Arabian Gulf Region: Clinical results of the Gulf FH Registry

2021

مقال في مجلة | PLOS | PLoS One

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema

2019

مقال في مجلة | ELSEVIER | Journal of Infection and Public Health

Prevalence of bleeding symptoms among young adults in Saudi Arabia, a national survey

2021

مقال في مجلة | Lippincott | MEDICINE

The Gulf Familial Hypercholesterolemia Registry (Gulf FH): Design, Rationale and Preliminary Results

2018

مقال في مجلة | Bentham Science Publishers | Current Vascular Pharmacology

The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing

2020

مقال في مجلة | Frontiers | Frontiers in Genetics

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

2019

مقال في مجلة | Spandidos Publications | ONCOLOGY LETTERS

Strategies for Vaccination: Conventional Vaccine Approaches Versus New-Generation Strategies in Combination with Adjuvants

2021

مقال في مجلة | MDPI | Pharmaceutics

Effects of mineral trioxide aggregate, calcium hydroxide, biodentine and Emdogain on osteogenesis, Odontogenesis, angiogenesis and cell viability of dental pulp stem cells

2019

مقال في مجلة | BMC | BMC Oral Health

EGFRvIII expression and isocitrate dehydrogenase mutations in patients with glioma

2020

مقال في مجلة | SPANDIDOS PUBL LTD | Oncology Letters

Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes

2021

مقال في مجلة | HINDAWI LTD | DISEASE MARKERS

Strategies for Vaccination: Conventional Vaccine Approaches Versus New-Generation Strategies in Combination with Adjuvants

2021

مقال في مجلة | MDPI | PHARMACEUTICS

The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing

2020

مقال في مجلة | FRONTIERS MEDIA SA | FRONTIERS IN GENETICS

The Fetal Mouse Is a Sensitive Genotoxicity Model That Exposes Lentiviral-associated Mutagenesis Resulting in Liver Oncogenesis

2013

مقال في مجلة | CELL PRESS | Molecular Therapy

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema.

2020

مقال في مجلة | Elsevier | Journal of Infection and Public Health

Xanthomas Can Be Misdiagnosed and Mistreated in Homozygous Familial Hypercholesterolemia Patients: A Call for Increased Awareness Among Dermatologists and Health Care Practitioners.

2020

مقال في مجلة | UBIQUITY PRESS LTD | Global Heart

The Gulf Familial Hypercholesterolemia Registry (Gulf FH): Design, Rationale and Preliminary Results.

2019

مقال في مجلة | BENTHAM SCIENCE PUBL LTD | Current Vascular Pharmacology

Identification of six novel factor viii gene variants using next generation sequencing and molecular dynamics simulation.

2019

مقال في مجلة | The Polish Biochemical Society and the Polish Academy of Sciences | ACTA Biochimica Polonica

Novel combined variants of LDLR and LDLRAP1 genes causing severe familial hypercholesterolemia.

2018

مقال في مجلة | Elsevier IRELAND LTD | Atherosclerosis

Next generation DNA sequencing of atypical choroid plexus papilloma of brain: Identification of novel mutations in a female patient by Ion Proton.

2019

مقال في مجلة | SPANDIDOS PUBL LTD | Oncology Letters

Microchimeric fetal cells cluster at sites of tissue injury in lung decades after pregnancy.

2008

مقال في مجلة | PMID: 18339261 | Reprod Biomed Online

Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3.

2013

مقال في مجلة | SPRINGER HEIDELBERG | Biotech3

Umbilical cord blood mesenchymal stromal cells are neuroprotective and promote regeneration in a rat optic tract model.

2009

مقال في مجلة | PMID: 19320003 | Exp Neurol

Rat neurosphere cells protect axotomized rat retinal ganglion cells and facilitate their regeneration.

2009

مقال في مجلة | doi: 10.1089/neu.2008-0801 | J Neurotrauma

Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype.

2009

مقال في مجلة | DOI: 10.4161/cc.8.7.8121 | Cell Cycle

Reduction of aGVHD using chicken antibodies directed against intestinal pathogens in a murine model.

2017

مقال في مجلة | AMERICAN SOCIETY OF HEMATOLOGY | Blood

Evidence of trem2 variant associated with triple risk of Alzheimer's disease

2014

مقال في مجلة | PUBLIC LIBRARY SCIENCE | PLoS One

Next generation sequencing to identify novel genetic variants causative of autosomal dominant familial hypercholesterolemia associated with increased risk of coronary heart disease.

2015

مقال في مجلة | Elsevier | Gene

Release of Vesicular Stomatitis Virus Spike Protein G-Pseudotyped Lentivirus from the Host Cell Is Impaired upon Low-Density Lipoprotein Receptor Overexpression.

2015

مقال في مجلة | AMERICAN SOCIETY OF MICROBIOLOGY | J Virol

Identification of a recurrent frameshift mutation at the LDLR exon 14 (c.2027delG, p.(G676Afs*33)) causing familial hypercholesterolemia in Saudi Arab homozygous children.

2016

مقال في مجلة | ACADEMIC PRESS INC ELSEVIER SCIENCE | Genomics

Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model.

2016

مقال في مجلة | BioMed Central | Journal of Experimental & Clinical Cancer Research

Next-generation sequencing for molecular diagnosis of autosomal recessive polycystic kidney disease.

2016

مقال في مجلة | Elsevier | Gene

Functional alterations due to amino acid changes and evolutionary comparative analysis of ARPKD and ADPKD genes.

2016

مقال في مجلة | Elsevier | Genomics Data

Phytosterols as a natural anticancer agent: Current status and future perspective.

2017

مقال في مجلة | TAYLOR & FRANCIS INC | Biomedicine & Pharmacotherapy

DNA mismatch repair MSH2 gene-based SNP associated with different populations.

2014

مقال في مجلة | SPRINGER HEIDELBERG | Molecular Genetics and Genomics

Compound heterozygous LDLR variant in severely affected familial hypercholesterolemia patient.

2016

مقال في مجلة | ACTA BIOCHIMICA POLONICA | Acta Biochim Pol

Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice

2008

مقال في مجلة | doi: 10.1016/j.ymthe.2005.10.003 | Molecular Therapy

Designing Lentiviral Gene Vectors. In Viral Gene Therapy Book

2011

Official government website of the Government of Kingdom of Saudi Arabia

Link to official Saudi websites end with edu.sa

Government websites use the HTTPS protocol for encryption and security.

CV

Qualifications

Scientific Research

Books