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Sharaf Ezzat Sharaf Sharaf
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Sharaf Ezzat Sharaf Sharaf
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Sharaf Ezzat Sharaf Sharaf

CV

Qualifications

الدكتوراه

2016

العلوم الصيدلية

جامعة سري | بريطانيا

الماجستير

2013

العلوم الصيدلية

جامعة سري | بريطانيا

البكالوريوس

1428

طب المختبرات

جامعة ام القرى | المملكة العربية السعودية

Scientific Research

Beyond PARP-HDAC inhibition: mechanistic rationale and medicinal chemistry insights from single to shared-target strategies

2026

مقال في مجلة | ACADEMIC PRESS INC ELSEVIER SCIENCE | Bioorganic Chemistry

أكثر

Computational screening of repurposed drugs targeting lactoferrin for neurodegenerative diseases

2025

مقال في مجلة | SAGE PUBLICATIONS LTD | JOURNAL OF ALZHEIMERS DISEASE

أكثر

Virtual screening and molecular dynamics simulations identify repurposed drugs as potent inhibitors of Histone deacetylase 1: Implication in cancer therapeutics

2024

مقال في مجلة | PUBLIC LIBRARY SCIENCE | PLoS One

أكثر

Unveiling Cathepsin B inhibition with repurposed drugs for anticancer and anti- Alzheimer’s drug discovery

2024

مقال في مجلة | PUBLIC LIBRARY SCIENCE | PLoS One

أكثر

Repurposed drugs as histone deacetylase 8 inhibitors: Implications in cancer and neuropathological conditions

2024

مقال في مجلة | FRONTIERS MEDIA SA | FRONTIERS IN PHARMACOLOGY

أكثر

Assessment of Knowledge, Attitude, and Practice of Therapeutic Drug Monitoring Among Hospital Pharmacists in Saudi Arabia

2024

مقال في مجلة | WILEY-HINDAWI | INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

أكثر

ROS1 kinase inhibition reimagined: identifying repurposed drug via virtual screening and molecular dynamics simulations for cancer therapeutics

2024

مقال في مجلة | FRONTIERS MEDIA SA | Frontiers in Chemistry

أكثر

Comprehensive spectroscopic and computational insight into the binding of vanillin with human transferrin: targeting neuroinflammation in Alzheimer’s disease therapeutics

2024

مقال في مجلة | FRONTIERS MEDIA SA | Frontiers in Pharmacology

أكثر

Unlocking therapeutic potential: computational insights into TREM2 protein targeting with FDA-approved drugs for neurodegeneration

2024

مقال في مجلة | TAYLOR & FRANCIS INC | JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

أكثر

Evaluation of binding mechanism of dietary phytochemical, capsaicin, with human transferrin: targeting neurodegenerative diseases therapeutics

2024

مقال في مجلة | FRONTIERS MEDIA SA | Frontiers in Pharmacology

أكثر

Evaluating Adherence to Therapeutic Drug Monitoring Guidelines for Gentamicin in Neonatal Care: A Retrospective Study at the Maternity and Children’s Hospital in Makkah

2024

مقال في مجلة | MDPI | CHILDREN-BASEL

أكثر

Targeting Sirtuin 1 for therapeutic potential: Drug repurposing approach integrating docking and molecular dynamics simulations

2023

مقال في مجلة | PUBLIC LIBRARY SCIENCE | PLOS ONE

أكثر

Unveiling Phytoconstituents with Inhibitory Potential Against Tyrosine-Protein Kinase Fyn: A Comprehensive Virtual Screening Approach Targeting Alzheimer’s Disease

2023

مقال في مجلة | IOS PRESS | JOURNAL OF ALZHEIMERS DISEASE

أكثر

Identifying B-secretase 1 (BACE1) inhibitors from plant-based compounds: an approach targeting Alzheimer’s therapeutics employing molecular docking and dynamics simulation

2023

مقال في مجلة | SPRINGER | MOLECULAR DIVERSITY

أكثر

Unveiling promising inhibitors of superoxide dismutase 1 (SOD1) for therapeutic interventions

2023

مقال في مجلة | ELSEVIER | International Journal of Biological Macromolecules

أكثر

G Protein-coupled Receptors (GPCRs) as Potential Therapeutics for Psychiatric Disorders

2023

مقال في مجلة | BENTHAM SCIENCE PUBL | CNS & Neurological Disorders - Drug Targets

أكثر

Linagliptin and Empagliflozin Inhibit Microtubule Affinity Regulatory Kinase 4: Repurposing Anti-Diabetic Drugs in Neurodegenerative Disorders Using In Silico and In Vitro Approaches

2023

مقال في مجلة | AMER CHEMICAL SOC | ACS OMEGA

أكثر

A virtual screening investigation to identify bioactive natural compounds as potential inhibitors of cyclin-dependent kinase 9

2022

مقال في مجلة | TAYLOR & FRANCIS INC | JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

أكثر

Mechanistic Insight into the Binding of Huperzine a with Human Transferrin: Computational, Spectroscopic and Calorimetric Approaches

2022

مقال في مجلة | AMER CHEMICAL SOC | ACS OMEGA

أكثر

Identification of 11-Hydroxytephrosin and Torosaflavone A as Potential Inhibitors of 3-Phosphoinositide-Dependent Protein Kinase 1 (PDPK1): Toward Anticancer Drug Discovery

2022

مقال في مجلة | MDPI | BIOLOGY

أكثر

Computational insight into the binding of bryostatin 1 with ferritin: implication of natural compounds in Alzheimer’s disease therapeutics

2022

مقال في مجلة | TAYLOR & FRANCIS INC | JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

أكثر

Inhibition of Microtubule Affinity Regulating Kinase 4 by Metformin: Exploring the Neuroprotective Potential of Antidiabetic Drug through Spectroscopic and Computational Approaches

2022

مقال في مجلة | MDPI | MOLECULES

أكثر

Death-Associated Protein Kinase 3 Inhibitors Identified by Virtual Screening for Drug Discovery in Cancer and Hypertension

2022

مقال في مجلة | OMICS | A Journal of Integrative Biology

أكثر

Exploring binding mechanism of naringenin to human transferrin using combined spectroscopic and computational methods: Towards therapeutic targeting of neurodegenerative diseases

2022

مقال في مجلة | Elsevier | Journal of Molecular Liquids

أكثر

Inhibition of PDK3 by artemisinin, a repurposed antimalarial drug in cancer therapy

2022

مقال في مجلة | Elsevier | Journal of Molecular Liquids

أكثر

Implications of tempol in pyruvate dehydrogenase kinase 3 targeted anticancer therapeutics: Computational, spectroscopic, and calorimetric studies

2022

مقال في مجلة | Elsevier | Journal of Molecular Liquids

أكثر

Mechanistic insight into the binding between Ferritin and Serotonin: Possible implications in neurodegenerative diseases

2022

مقال في مجلة | ELSEVIER | Journal of Molecular Liquids

أكثر

Knowledge, Attitude, and Practice of Bee Venom Acupuncture Therapy on Rheumatoid Arthritis Among Patients in Saudi Arabia

2022

مقال في مجلة | Dovepress | International Journal of General Medicine

أكثر

Hypertension self-management and antihypertensive prevalence amid patients in Saudi Arabia via knowledge, attitude, and practice assessment

2021

مقال في مجلة | MedCrave Publishing | International Journal of Family & Community Medicine

أكثر

Obesity self-management: knowledge, attitude, practice, and pharmaceutical use among healthy obese individuals in Saudi Arabia

2021

مقال في مجلة | MedCrave Publishing | International Journal of Family & Community Medicine

أكثر

Biochemical computational therapeutic approach towards the discovery of natural product noncovalent inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase

2021

مقال في مجلة | MedCrave Publishing | Pharmacy & Pharmacology International Journal

أكثر

Knowledge, attitude, practice, and pharmaceutical outcomes of type 2 diabetes mellitus self-management among patients in Makkah Region, Saudi Arabia

2021

مقال في مجلة | Sharaf E. Sharaf | Pharmacy and Pharmacology International Journal

أكثر

Lixisenatide Reduces Chylomicron Triacylglycerol by Increased Clearance

2018

مقال في مجلة | Sharaf E. Sharaf | Journal of Clinical Endocrinology & Metabolism

أكثر

HDL-apoA-I kinetics in response to 16 wk of exercise training in men with nonalcoholic fatty liver disease

2020

مقال في مجلة | Sharaf E. Sharaf | American Journal of Physiology Endocrinology and Metabolism

أكثر

Achievements

Registering an approved innovative trademark

الهيئة السعودية للملكية الفكرية - جامعة أم القرى

Societies

الجمعية الصيدلية السعودية

2025 – 2030

ممثل مدينة مكة المكرمة | عضوية عاملة | المنطقة الغربية بالمملكة العربية السعودية