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20250417892
Mahmoud Zaki Mohamed El Readi
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Mahmoud Zaki Mohamed El Readi
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Mahmoud Zaki Mohamed El Readi

CV

Qualifications

الدكتوراه

2011

‏الكيمياء الحيوية

جامعة هايدلبرج | المانيا

الدكتوراه

2011

‏الكيمياء الحيوية

جامعة هايدلبرج-المانيا | المانيا

الماجستير

2005

‏الكيمياء الحيوية

جامعة أسيوط | جمهورية مصر

البكالوريوس

2000

‏الصيدلة

جامعة الازهر | جمهورية مصر

Scientific Research

QUERCETIN AND COENZYME Q10: A COMPARISON STUDY OF THEIR HEPATOPROTECTIVE EFFECTS IN PARACETAMOL-INDUCED HEPATOTOXIC RATS

2024

مقال في مجلة | African Journal of Biomedical Research, | African Journal of Biomedical Research,

Isolation and Characterization of Highly Active Uricase from Alcaligenes spp. Strain UR1

2026

مقال في مجلة | De Gruyter Poland | Polish Journal of Microbiology

Rosemary reduced estrogen receptor (ESR1) protein mediated cycle arrest and apoptosis: A potential hormonal dependent anticancer mechanism of the plant in the MCF-7 breast cancer cells

2025

مقال في مجلة | Pakistan journal of pharmaceutical sciences | Pakistan journal of pharmaceutical sciences

Protective effects of oral pharmaceutical solution of fucoxanthin against paracetamol-induced liver injury: modulation of drug-metabolizing enzymes, oxidative stress, and apoptotic pathways in rats

2026

مقال في مجلة | Taylor & Francis | Drug Development and Industrial Pharmacy

Assessment of oxidative stress biomarkers in healthcare workers exposed to low dose of ionizing radiation in Saudi Arabia

2025

مقال في مجلة | ScinceDirect | Journal of Radiation Research and Applied Sciences

Mahmoud Zaki El-Readi Mahmoud Zaki El-Readi Design and synthesis of multitarget triazinoindole derivatives with potent antiproliferative activity: Targeting EGFR, SIRT1, MDM2, Hsp90, PI3K, p53, and caspase-9

2024

مقال في مجلة | Academic Press | Bioorganic Chemistry

أكثر

Hydrogel films of chitosan and eucalyptus oil enhance wound healing in rats

2024

مقال في مجلة | Scientific Scholar | Arabian Journal of Chemistry

أكثر

Ferrite/curcumin hybrid nanocomposite formulation: Physicochemical characterization, anticancer activity, and apoptotic and cell cycle analyses in skin cancer cells

2024

مقال في مجلة | De Gruyter | Nanotechnology Reviews

أكثر

Design, synthesis, and antiproliferative efficacy of an innovative series of triazino[5,6-b]indole derivatives targeting EGFR, CD1, Hsp90, PI3K, and ERK/AKT as key molecular targets in cancer therapy

2024

مقال في مجلة | ScinceDirect | European Journal of Medicinal Chemistry

أكثر

Azacitidine alone or with metformin reduces insulin resistance in high-fat diet diabetic rats. 9th annual conferences of SSCC & 5th international meeting on clinical chemistry and laboratory medicine

2023

ورقة مؤتمر | . 9th annual conferences of SSCC & 5th international meeting on clinical chemistry and laboratory medicine | . 9th annual conferences of SSCC & 5th international meeting on clinical chemistry and laboratory medicine

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats

2023

مقال في مجلة | MDPI | marine drugs

أكثر

Concurrent alteration in the inflammatory biomarkers at gene and protein level by fucoxanthin in liver injury rat

2024

مقال في مجلة | Elsevier B.V | Clinica Chimica Acta

أكثر

Antimicrobial Agent Based on Ca-Doped ZnO Nanopowders

2023

مقال في مجلة | Wiley | physica status solidi (a)

أكثر

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats

2024

مقال في مجلة | MDPI | Marine

أكثر

Doxorubicin-sanguinarine nanoparticles: formulation and evaluation of breast cancer cell apoptosis and cell cycle

2024

مقال في مجلة | Taylor & Francis Online | Drug Development and Industrial Pharmacy

أكثر

Concurrent alteration in the inflammatory biomarkers at gene and protein level by fucoxanthin in liver injury rat

2024

مقال في مجلة | Elsevier B.V | Clinica Chimica Acta

أكثر

Concurrent alteration in the inflammatory biomarkers at gene and protein level by fucoxanthin in liver injury rat

2024

مقال في مجلة | Elsevier B.V | Clinica Chimica Acta

أكثر

Microbial Uricase and its Unique Potential Applications

2024

مقال في مجلة | Sciendo | Advancements of Microbiology

أكثر

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2024

مقال في مجلة

protective effect of BTK targeting induce liver in murine

2584

ورقة مؤتمر | Saudi society of clinical chemistry | Saudi society of clinical chemistry

Protective effect of Fucoxanthin on Paracetamol-induced hepatotoxicity in rats

2583

ورقة مؤتمر | international conference of Saudi society of clinical chemistry | international conference of Saudi society of clinical chemistry

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin

2021

مقال في مجلة | MDPI | molecules

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

2583

مقال في مجلة | Nature Publishing Group UK | Scientific Reports

Short-term treatment of metformin and glipizide on oxidative stress, lipid profile and renal function in a rat model with diabetes mellitus

2583

مقال في مجلة | MDPI | Applied Sciences

In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network

2583

مقال في مجلة | MDPI | cancers

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway

2583

مقال في مجلة | Elsevier B.V | Life Sciences

Phytochemical profiling, molecular docking, and in vitro anti-hepatocellular carcinoid bioactivity of Suaeda vermiculata extracts

2583

مقال في مجلة | Elsevier B.V | Arabian Journal of Chemistry

Cinnamaldehyde-Based Self-Nanoemulsion (CA-SNEDDS) accelerates wound healing and exerts antimicrobial, antioxidant, and anti-inflammatory effects in rats’ skin burn model

2583

مقال في مجلة | MDPI | molecules

Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males

2584

مقال في مجلة | Frontiers Media SA | Frontiers in Endocrinology

Functional Low-fat Set Yogurt Enhanced with Microbial Exo-polysaccharides-mediated Anticancer Activity

2584

مقال في مجلة | Journal of Pure & Applied Microbiology | Journal of Pure & Applied Microbiology

Liver Injury in Favipiravir-Treated COVID-19 Patients: Retrospective Single-Center Cohort Study

2584

مقال في مجلة | MDPI | Tropical Medicine and Infectious Disease

أكثر

In Vitro Anticancer and Antibacterial Activities of the Essential Oil of Forsskal’s Basil Growing in Extreme Environmental Conditions

2584

مقال في مجلة | MDPI | Life

The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study

2584

مقال في مجلة | Churchill Livingstone | Complementary Therapies in Medicine

Metformin and thymoquinone co‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells

1614

مقال في مجلة | John Wiley & Sons, Inc. | BioFactors

Patterns of acute poisoning for children during outbreak of Corona virus in Makkah region Saudi Arabia

2584

مقال في مجلة | Frontiers Media SA | Frontiers in pediatrics

أكثر

Development of Transdermal Oleogel Containing Olmesartan Medoxomil: Statistical Optimization and Pharmacological Evaluation

2584

مقال في مجلة | MDPI | Pharmaceutics

أكثر

Cymbopogon citratus and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters

2023

مقال في مجلة | MDPI | molecules

أكثر

Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat

2023

مقال في مجلة | Elsevier B.V | Journal of Trace Elements in Medicine and Biology

أكثر

Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells

2020

مقال في مجلة | MDPI | Molecules

أكثر

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway

2022

مقال في مجلة | ELSEVIER | Life Sciences

أكثر

Salvia officinalis L., Constituents, Hepatoprotective Activity, and Cytotoxicity Evaluations of the Essential Oils Obtained from the Fresh and Differently Timed Dried Herbs: A Comparative Analysis. Molecules, 26(19), 5757; https://doi.org/10.3390/molecules26195757 (2021).

2021

مقال في مجلة | MDBI | Molecules

أكثر

Beta 2 microglobulin correlates with oxidative stress in elderly. Experimental Gerontology, 150, 111359 (2021).

2021

مقال في مجلة | NCBI | Exp Gerontol .

أكثر

Short-term treatment of metformin and glipizide on oxidative stress, lipid profile, and renal function in a rat model with diabetes mellitus. Appl. Sci., 12(4); https://doi.org/10.3390/app12042019

2022

مقال في مجلة | MDBI | Applied science

أكثر

Thymoquinone, but Not Metformin, Protects against Gentamicin-Induced Nephrotoxicity and Renal Dysfunction in Rats. Applied Science, 11, (9), 3981 (2021).

2021

مقال في مجلة | MDBI | Applied science

أكثر

LC-MS Profiled Chemical Constituents, Molecular Modeling, and in-vitro Bioactivity Evaluations of Suaeda vermiculata Extracts as Anti-Hepatocellular Carcinoma Preparation: Assessment of the Constituents’ Role, and Receptor Docking Feasibility Based Activity Projections. Submitted to Arabian Journal of Chemistry.

2021

مقال في مجلة | MDBI | Plants

أكثر

Is Vitamin D Deficiency a Risk Factor for Helicobacter Pylori Eradication Failure? Clin Lab, 67, (2) (2021).

2021

مقال في مجلة | NCBI | Clin.Lab.

أكثر

Roles of Suaeda vermiculata Aqueous-Ethanolic Extract, Its Subsequent Fractions, and the Isolated Compounds in Hepatoprotection against Paracetamol-Induced Toxicity as Compared to Silymarin, Oxidative Medicine and Cellular Longevity, Article ID 6174897, https://doi.org/10.1155/2021/6174897 (2021).

2021

مقال في مجلة | MDBI | Oxid Med Cell Longev

أكثر

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin

2021

مقال في مجلة | MDBI | Molecules

أكثر

In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D 3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network

2022

مقال في مجلة | MDBI | cancers

أكثر

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

2022

مقال في مجلة | NCBI | scientific report

أكثر

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway." Life Sciences (2022): 120442.

2022

مقال في مجلة | NCBI | life Science

أكثر

Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites. Frontiers in Pharmacology, 12, (942) (2021).

2021

مقال في مجلة | Front. Pharmacol | Front. Pharmacol

أكثر

Potential Predictors of Poor Prognosis among Severe COVID-19 Patients: A Single-Center Study. Canadian Journal of Infectious Diseases and Medical Microbiology, 6656092 (2021).

2021

مقال في مجلة | NCBI | Can J Infect Dis Med Microbiol .

أكثر