CV | Basem Amr Ahmad Refaat | Umm Al-Qura University

Qualifications

الدكتوراه

2009

الطب العام

كلية الطب جامعة شيفلد | بريطانيا

الماجستير

2004

العلوم الطبية الأساسية

كلية الطب, جامعة شيفلد | بريطانيا

البكالوريوس

2001

الجراحة العامة

كلية الطب جامعة عين شمس | جمهورية مصر

دبلوم

2007

جامعة شيفلد | بريطانيا

Scientific Research

Increased protein expression of interleukin-10 and its signalling molecules in colon cancer progression: potential prognostic and therapeutic targets

2025

مقال في مجلة | Springer | Discover Oncology

Prevalence of Hypertension Risk Factors Among Young Female Students of Umm Al-Qura University, Makkah, Saudi Arabia: A Cross-Sectional Study

2025

مقال في مجلة | JPMS PUBL | Journal of Pioneering Medical Sciences

Protective effects of oral pharmaceutical solution of fucoxanthin against paracetamol-induced liver injury: modulation of drug-metabolizing enzymes, oxidative stress, and apoptotic pathways in rats

2025

مقال في مجلة | Taylor & Francis | Drug Development and Industrial Pharmacy

IL-10-Directed Cancer Immunotherapy: Preclinical Advances, Clinical Insights, and Future Perspectives

2025

مقال في مجلة | MDPI | Cancers

Polydatin Mitigates Lead-Induced Nephropathy by Modulating Oxidative Stress, Inflammation, and the AMPK/AKT/Nrf2 Pathway in Rats

2025

مقال في مجلة | Springer | Biological Trace Element Research

Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation

2025

مقال في مجلة | Springer | Journal of the Egyptian National Cancer Institute

The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications

2024

مقال في مجلة | ELSEVIER | Phytomedicine Plus

Comparative impacts of Saudi Arabian and Egyptian Aspergillus flavus-associated Aflatoxin B1 on rats

2024

مقال في مجلة | Mushroom Research Foundation | Current Research in Environmental & Applied Mycology (Journal of Fungal Biology)

Cytotoxic activity, selectivity, and clonogenicity of fruits and resins of Saudi medicinal plants against human liver adenocarcinoma

2024

مقال في مجلة | AboutScience | Drug Target Insights

Enhanced hepatoprotective effects of empagliflozin and vitamin D dual therapy against metabolic dysfunction-associated steatohepatitis in mice by boosted modulation of metabolic, oxidative stress, and inflammatory pathways

2024

مقال في مجلة | Wiley | International Journal of Experimental Pathology

Saffron (Crocus Sativus Linnaeus) based protection against Aflatoxin B1 induced organ damage in rats

2024

مقال في مجلة | University of Ljubljana Press | Acta Biologica Slovenica

Concurrent alteration in the inflammatory biomarkers at gene and protein level by fucoxanthin in liver injury rat

2024

مقال في مجلة | Elsevier | CLINICA CHIMICA ACTA

Saffron (Crocus sativus L.) based protection against Aflatoxin B1 induced haematological and organ damages in rats

2025

مقال في مجلة | University of Ljubljana Press | ACTA BIOLOGICA SLOVENICA

The Quality of Blood Donation Services and Its Association with Blood Donors’ Trust and Loyalty at Makkah Blood Donation Centers in Saudi Arabia: A Cross-Sectional Study

2023

مقال في مجلة | MDPI | Healthcare

Seroprevalence of transfusion-transmitted infections among blood donors in Makkah, Saudi Arabia

2023

مقال في مجلة | J INFECTION DEVELOPING COUNTRIES | Journal of Infection in Developing Countries

Concurrent alteration in the inflammatory biomarkers at gene and protein level by fucoxanthin in liver injury rat

2024

ورقة مؤتمر | Elsevier | Clinica Chimica Acta

Seroprevalence of transfusion-transmitted infections among blood donors in Makkah, Saudi Arabia

2024

مقال في مجلة | J INFECTION DEVELOPING COUNTRIES | The Journal of Infection in Developing Countries (JIDC)

In-vitro Cytotoxicity Investigations for Phytoconstituents of Saudi Medicinal Plants With Putative Ocular Effects

2024

مقال في مجلة | SAGE PUBLICATIONS INC | Integrative Cancer Therapies

Doxorubicin-sanguinarine nanoparticles: formulation and evaluation of breast cancer cell apoptosis and cell cycle

2024

مقال في مجلة | TAYLOR & FRANCIS LTD | Drug Development and Industrial Pharmacy

Improved Glycaemic Control and Nephroprotective Effects of Empagliflozin and Paricalcitol Co-Therapy in Mice with Type 2 Diabetes Mellitus

2023

مقال في مجلة | MDPI | International Journal of Molecular Sciences

The protective effects of Vitamin D against Cadmium-induced nephrotoxicity

2023

مقال في مجلة | Elsevier | The Journal of Trace Elements and Minerals

Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats

2023

مقال في مجلة | MDPI | Marine Drugs

Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat

2023

مقال في مجلة | Elsevier | Journal of Trace Elements and Minerals

The Quality of Blood Donation Services and Its Association with Blood Donors’ Trust and Loyalty at Makkah Blood Donation Centers in Saudi Arabia: A Cross-Sectional Study

2023

مقال في مجلة | MDPI | Healthcare

Protective Effects of BTK Targeting in induced Liver Injury in Murine

2023

ورقة مؤتمر | Saudi Society for Clinical Chemistry | Saudi Society for Clinical Chemistry

Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats

2016

مقال في مجلة | DOVE MEDICAL PRESS LTD | Drug Design Development and Therapy

Seroprevalence of asymptomatic dengue virus infection and its antibodies among healthy/eligible saudi blood donors: findings from holy makkah city

2017

مقال في مجلة | SAGE Publications | Virology: Research and Treatment

A comparative study between the therapeutic efficacy of vitamin D3 and its analogue, paricalcitol, in the treatment of colon cancer in rat

2019

ورقة مؤتمر | AMER ASSOC CANCER RESEARCH | CANCER RESEARCH

The expression profiles of activins and follistatin at the different stages of colorectal cancer

2020

ورقة مؤتمر | AMER ASSOC CANCER RESEARCH | CANCER RESEARCH

Characterization of activins and their related molecules in colorectal cancer according to clinical stage, tumor sidedness and the expression of PI3K/mTOR proteins

2021

ورقة مؤتمر | AMER ASSOC CANCER RESEARCH | CANCER RESEARCH

Exploring the anti-cancer activities of 5-Fluorouracil, metformin, and calcitriol single, dual, and triple therapies against colon cancer cells in vitro: The role of PI3K/Akt/mTOR pathway

2022

ورقة مؤتمر | AMER ASSOC CANCER RESEARCH | CANCER RESEARCH

Insights from the molecular docking analysis of EGFR antagonists

2023

مقال في مجلة | BIOMEDICAL INFORMATICS | Bioinformation

Green-synthesized nanoparticles and their therapeutic applications: A review

2023

مقال في مجلة | De Gruyter | Green Processing and Synthesis

Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

2023

مقال في مجلة | Frontiers | Frontiers in Endocrinology

Vitamin D3 Alleviates Non-Alcoholic Fatty Liver Disease in Rats by Inhibiting Hepatic Oxidative Stress and Inflammation Via SREBP-1-c/PPARα-NF-κB/IR-S2 Signaling Pathway

2023

مقال في مجلة | Frontiers | Frontiers in Pharmacology

Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat

2023

مقال في مجلة | Elsevier | Journal of Trace Elements in Medicine and Biology

Cymbopogon citratus and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters

2023

مقال في مجلة | MDPI | MOLECULES

Hepatoprotective and Neuroprotective Effects of Naringenin against Lead-Induced Oxidative Stress, Inflammation, and Apoptosis in Rats

2023

مقال في مجلة | MDPI | Biomedicines

Patterns of acute poisoning for children during outbreak of Corona virus in Makkah region Saudi Arabia

2023

مقال في مجلة | Frontiers | Frontiers in Pediatrics

Metformin and thymoquinone co-treatment enhance 5-fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells

2023

مقال في مجلة | Wiley | Biofacors

Antioxidative and Anti-Inflammatory Protective Effects of β-Caryophyllene against Amikacin-Induced Nephrotoxicity in Rat by Regulating the Nrf2/AMPK/AKT and NF-κB/TGF-β/KIM-1 Molecular Pathways

2022

مقال في مجلة | Hindawi | Oxidative Medicine and Cellular Longevity

Deferasirox and vitamin D3 co-therapy mitigates iron-induced renal injury by enhanced modulation of cellular anti-inflammatory, anti-oxidative stress, and iron regulatory pathways in rat

2022

مقال في مجلة | ELSEVIER | TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males

2022

مقال في مجلة | Frontiers | Frontiers in Endocrinology

The prevalence of Chlamydia trachomatis and Mycoplasma genitalium tubal infections and their effects on the expression of IL-6 and leukaemia inhibitory factor in Fallopian tubes with and without an ectopic pregnancy

2016

مقال في مجلة | SAGE PUBLICATIONS INC | Innate Immunity

The fibrolytic potentials of vitamin D and thymoquinone remedial therapies: insights from liver fibrosis established by CCl4 in rats

2016

مقال في مجلة | ٍSpringer | Journal of Translational Medicine

Characterisation of vitamin D-related molecules and calcium-sensing receptor in human Fallopian tube during the menstrual cycle and in ectopic pregnancy

2016

مقال في مجلة | ٍSpringer | Cell and Tissue Research

Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer

2016

مقال في مجلة | ٍSpringer | BMC Cancer

Thymoquinone potentiates chemoprotective effect of Vitamin D3 against colon cancer: a pre-clinical finding

2017

مقال في مجلة | E-Centry Publishing | American Journal of Translational Research

Vitamin D alleviates lead induced renal and testicular injuries by immunomodulatory and antioxidant mechanisms in rats

2018

مقال في مجلة | Nature | Scientific Reports

Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney

2018

مقال في مجلة | Sage | Journal of Histochemistry and Cytochemistry

Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic molecules

2018

مقال في مجلة | ELSEVIER | BBA Molecular Basis of Disease

Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells

2020

مقال في مجلة | MDPI | Molecules

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway

2022

مقال في مجلة | ELSEVIER | Life Sciences

Salvadora persica extract attenuates cyclophosphamide-induced hepatorenal damage by modulating oxidative stress, inflammation and apoptosis in rats

2022

مقال في مجلة | ELSEVIER | Journal of Integrative Medicine

Antioxidative and Anti-Inflammatory Protective Effects of β-Caryophyllene against Amikacin-Induced Nephrotoxicity in Rat by Regulating the Nrf2/AMPK/AKT and NF-κB/TGF-β/KIM-1 Molecular Pathways

2022

مقال في مجلة | Hindawi | Oxidative Medicine and Cellular Longevity

Associations of Clinical Factors and Blood Groups With the Severity of COVID-19 Infection in Makkah City, Saudi Arabia

2022

مقال في مجلة | Frontiers | Frontiers in Cellular and Infection Microbiology

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin

2021

مقال في مجلة | MDPI | Molecules

Hydrogel films of methanolic Mentha piperita extract and silver nanoparticles enhance wound healing in rats with diabetes Type I

2022

مقال في مجلة | Taylor and Francis | Journal of Taibah University for Science

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin

2021

مقال في مجلة | MDPI | Molecules

BTK targeting suppresses inflammatory genes and ameliorates insulin resistance

2021

مقال في مجلة | Springer | European Cytokine Network

Chemopreventive effects of vitamin D3 and its analogue, paricalcitol, in combination with 5-fluorouracil against colorectal cancer: The role of calcium signalling molecules

2021

مقال في مجلة | Elsevier | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Enhanced renoprotective actions of Paricalcitol and omega-3 fatty acids co-therapy against diabetic nephropathy in rat

2021

مقال في مجلة | Elsevier | Journal of Advanced Research

Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway

2022

مقال في مجلة | Elsevier | Life Sciences

In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network

2022

مقال في مجلة | MDPI | Cancers

Vitamin D3 enhances the effects of omega-3 oils against metabolic dysfunction-associated fatty liver disease in rat

2021

مقال في مجلة | Wiley | BioFactors

Protective antioxidative and anti-inflammatory actions of ?-caryophyllene against sulfasalazine-induced nephrotoxicity in rat

2022

مقال في مجلة | Sage | Experimental Biology and Medicine

Effects of supraphysiological vitamin D3 (cholecalciferol) supplement on normal adult rat ovarian functions

2021

مقال في مجلة | Springer | Histochemistry and Cell Biology

Profiling activins and follistatin in colorectal cancer according to clinical stage, tumour sidedness and Smad4 status

2021

مقال في مجلة | Frontiers | Pathol. Oncol. Res.

Factors Associated with Thyroid Disorders and Iodine Adequacy in Pregnant Saudi Women

2020

مقال في مجلة | ٍSpringer | Biological Trace Element Research

Iodine adequacy in reproductive age and pregnant women living in the Western region of Saudi Arabia

2020

مقال في مجلة | ٍSpringer | BMC Pregnancy and Childbirth

Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti?inflammatory actions by remodeling cellular calcium pathways

2020

مقال في مجلة | Wiley | Journal of Biochemical and Molecular Toxicology

The performances of serum activins and follistatin in the diagnosis of ectopic pregnancy: A prospective case-control study

2019

مقال في مجلة | ELSEVIER | Clinica Chimica Acta

Protective effect of Vitamin D3 against lead induced hepatotoxicity, oxidative stress, immunosuppressive and calcium homeostasis disorders in rat

2019

مقال في مجلة | ELSEVIER | Environmental Toxicology and Pharmacology

Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat

2019

مقال في مجلة | ELSEVIER | Free Radical Biology and Medicine

The remedial effect of Thymus vulgaris extract against lead toxicity-induced oxidative stress, hepatorenal damage, immunosuppression, and hematological disorders in rats

2019

مقال في مجلة | ٍSpringer | Environmental Science and Pollution Research

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CV

Qualifications

Scientific Research

Books

Achievements

Supervising Mawhiba program student