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Aromatic and Heterocyclic Chemistry

CHM2402
3 hours English

Aromatic and Heterocyclic Chemistry

Aromatic and Heterocyclic Chemistry
1 The definition of aromaticity: structure, bonding, and aromaticity in aromatic compounds
2 Nomenclature, physical, chemical properties, and electrophilic aromatic substitution reactions of benzene
3 Mechanism of electrophilic aromatic substitution and second electrophilic substitution (directing effect)
4 Nomenclature, physical, chemical properties, and preparations of aryl halides and different aromatic families according to functional groups including phenols, ethers, aromatic carbonyl compounds, aromatic carboxylic acids, and aromatic amines
5 Introduction to chemistry of polynuclear aromatic compounds
6 Classification of heterocyclic compounds
7 Nomenclature of heterocyclic compounds
8 Bonding, structure and aromaticity applied to heterocyclic compounds
9 Structure and reactivity of five and six-membered heterocyclic compounds
10 Synthesis and reactions of five membered rings and their benzo fused systems
11 Synthesis and reactions of six membered rings and their benzo fused systems
1.1 Mapped to: K1

Define aromaticity and the criteria for aromatic compounds, including the structure and bonding in such compounds.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.2 Mapped to: K2

Name and classify the aromatic compounds.

Teaching Strategy Lectures
Assessment Methods Quiz. Final and mid-term exam.
1.3 Mapped to: K1

State the physical and chemical properties of benzene and describe its electrophilic aromatic substitution reactions.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.4 Mapped to: K2

Identify the functional groups in aromatic compounds, including phenols, ethers, carbonyl compounds, carboxylic acids, sulphonic acids, and amines, and their nomenclature and preparations.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.5 Mapped to: K2

Outline the properties and chemical reactivity of polynuclear aromatic compounds.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.6 Mapped to: K1

Know the different methods for nomenclature of heterocyclic compounds containing oxygen, sulfur and nitrogen and How to draw the chemical structures

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.7 Mapped to: K2

State the principles of bonding, structure, and aromaticity as applied to heterocyclic compounds.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.8 Mapped to: K2

Classify heterocyclic compounds based on their structure and identify examples from each class.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
1.9 Mapped to: K2

List the synthetic methods for preparing five- and six-membered heterocyclic compounds and their benzo-fused systems.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exam.
2.1 Mapped to: S2

Demonstrate the ability to predict aromaticity in given compounds using Hückel’s rule and structural analysis.

Teaching Strategy Lectures Scientific discussion
Assessment Methods Assignments and activities Final and mid-term exam.
2.2 Mapped to: S2

Illustrate the differences in reactivity between heterocyclic and non-heterocyclic aromatic compounds using reaction mechanisms.

Teaching Strategy Lectures Scientific discussion
Assessment Methods Assignments and activities Final and mid-term exam.
2.3 Mapped to: S3

Evaluate the reactivity of aromatic compounds under varying electrophilic aromatic substitution conditions to optimize product yield.

Teaching Strategy Lectures Scientific discussion
Assessment Methods Assignments and activities Final and mid-term exam.
2.4 Mapped to: S3

Synthesize multi-functionalized aromatic and heterocyclic compounds using appropriate synthetic routes and reagents.

Teaching Strategy Lectures Scientific discussion
Assessment Methods Final and mid-term exam.
2.5 Mapped to: S1

Apply safety protocols and environmental awareness practices in handling chemicals and conducting laboratory experiments effectively and responsibly.

Teaching Strategy Lectures Lab work
Assessment Methods Continuous evaluation, during the performance of experiments
2.6 Mapped to: S1

Perform systematic procedures to identify aromatic hydrocarbons, aldehydes, ketones, phenols, carboxylic acids, esters, and amines, demonstrating proficiency in observation and analysis.

Teaching Strategy Lectures Lab work
Assessment Methods Lab exam
2.7 Mapped to: S1

Synthesize aromatic and heterocyclic compounds such as phthalimide, phthalylglycine, benzimidazole, and benzotriazole using appropriate laboratory techniques, ensuring accuracy and adherence to reaction protocols.

Teaching Strategy Lectures Lab work
Assessment Methods Lab exam
3.1 Mapped to: V1

Commit to following safety protocols and best practices while handling hazardous chemicals in practical applications of aromatic and heterocyclic chemistry.

Teaching Strategy Scientific discussion during lab work
Assessment Methods Class discussion. Assignment activities.
3.2 Mapped to: V2

Communicate the importance of aromatic and heterocyclic compounds in industrial, environmental, and pharmaceutical applications to diverse audiences.

Teaching Strategy Lectures
Assessment Methods Class discussion. Assignment activities.