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Main
UQU Programs
Industrial Chemistry

Chemotherapy

CHMI4412
Two hours English

Chemotherapy

Chemotherapy ()
CHMI3407 Organic Spectroscopy
Two hours One requisite
1 Introduction to chemotherapy: Common medicinal classifications, / principles of drug action
2 Metabolite agonist and antagonist
3 Prodrug and drug delivery
4 Structure-activity relationship (SARs) and Quantitative structure–activity relationships (QSARs)
5 Chemotherapy definition and classification / Antimicrobial agents / Anticancer agents
6 Antibiotic depending upon their range of effects (penicillin, synthesis of penicillin derivatives, penicillin V, penicillin G and synthesis of ampicillin from penicillin G)
7 Antibiotic depending upon antimicrobial action (sulfa drug, synthesis of sulfonamide derivatives, therapeutic uses, types of mode action)
8 Antiviral agents (chloroquine -synthesis -clinical uses- Zanamivir-synthesis) and vaccine common component
9 Anticancer agents / Cytotoxic (non-specific). / Targeted (specific)
10 Histamine and Antihistamines: Definition, classification and synthesis
11 Peptic ulcer disease: Classification, associated complications, and therapeutic approaches
12 Gout: Causes and treatment
13 Vitamins Vitamin B1 (deficiency and their sources) and Vitamin B6 (synthesis and their sources)
1.1 Mapped to: K1

Familiar with chemical basis of chemotherapy, including the classification and importants of it in medical field.

Teaching Strategy Lectures
Assessment Methods Final and mid-term exams
1.2 Mapped to: K2

Recoginze the various methods used for synthesizing of cytotoxic and targeted agents

Teaching Strategy Lectures
Assessment Methods Final and mid-term exams
2.1 Mapped to: S2

Explain principles of structure-activity relationships (SARs) and quantitative structure-activity relationships (QSARs)

Teaching Strategy Lectures
Assessment Methods Final and mid-term exams
2.2 Mapped to: S2

Compare and differentiate the mechanisms of action of various chemotherapeutic agents.

Teaching Strategy Lectures and scientific discussion
Assessment Methods Final and mid-term exams
2.3 Mapped to: S2

Summarize the different methods used to synthesis of various chemotherapeutic agents

Teaching Strategy Lectures
Assessment Methods Final and mid-term exams
2.4 Mapped to: S4

Demonstrate proficiency in writing, oral communication, and the use of ICT tools relevant to medicinal chemistry.

Teaching Strategy Lectures, web-based study library visits.
Assessment Methods Class discussion and Assignment activities
3.1 Mapped to: V1

Student will demonstrate commitment to professional and academic values, and ethics in the field of medicinal chemistry

Teaching Strategy web-based study library visits.
Assessment Methods Assignment activities
Assessment
Weight
Homework and activities
10%
Frist mid term exam
20%
Second mid term exam
20%
Final exam
50%
Total
100%